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NFNB Recombinant Protein

CAT: 0793-32-2605-20Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2605-20Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. NFNB Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-217 a.a.) and having a molecular mass of 26 kDa. The NFNB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. NFNB demonstrates the capability to reduce quinines. NFNB enzyme activates prodrugs in antibody directed enzyme prodrug therapy. NFNB reduces nitrofurazone, quinones and anti-tumor agent CB1954 (5- (aziridin-1-yl) -2,4-dinitrobenzamide) . The reduction of CB1954 results in the generation of cytotoxic species.
Product Name Alternative
DPRA||NFSB||NFSI||NTR.
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
1mg/mL solution containing 20mM Tris pH-8, 1mM DTT, 0.05M NaCl & 10% glycerol.
Storage Conditions
NFNB Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
Amino Acids
MGSSHHHHHH SSGLVPRGSH MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV AKSAAGNYVF NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV.

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