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HARS Recombinant Protein

CAT: 0793-32-2426-50Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0793-32-2426-50Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Source : Escherichia Coli. Histidyl-tRNA Synthetase Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 55 kDa. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Product Name Alternative
Histidyl-tRNA synthetase||EC 6.1.1.21||Histidine-tRNA ligase||HisRS||HRS||FLJ20491||JO-1||HARS.
Purification
Greater than 95.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Components
The protein solution contains 500mM NaCl and 10mM Tris (pH 8.0) and 6M Urea.
Storage Conditions
Histidyl-tRNA Synthetase although stable at 4°C for 3 weeks, should be stored below -18°C.Please prevent freeze-thaw cycles.

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