Products for Research Use Only
RegisterLogin

GUCA2B Recombinant Protein

CAT: 0793-32-2040-10Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0793-32-2040-10Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Source : Escherichia Coli. Prouroguanylin Human Recombinant is 10 kDa protein containing 88 amino acid residues of the human prouroguanylin and 2 additional amino acid residues.GPVYIQYQGF RVQLESMKKL SDLEAQWAPS PRLQAQSLLP AVCHHPALPQ DLQPVCASQE ASSIFKTLRT IANDDCELCV NVACTGCLThe Prouroguanylin is purified by proprietary chromatographic techniques. Prouroguanylin is a 112-amino-acid prohormone precursor of uroguanylin- mature biologically active 16-amino-acid peptide cleaved from its C-terminus. Guanylin binds to receptor-guanylate cyclases (CG-C) resulting in increased intracellular cGMP levels leading to CFTCR (Cystic Fibrosis Transmembrane Conductance Regulator) activation and subsequent rise in fluid and electrolyte secretion into the lumen.Prouroguanyline knock-out mice showed impaired renal excretion of external NaCl leading to elevated blood pressure independent of the level of diatary salt intake.Prouroguanylin is the predominant circulating molecular form found in circulation and in biological fluids.
Product Name Alternative
Guanylate cyclase activator 2B||UGN||GCAP-II||GUCA2B.
Purification
Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Components
Sterile filtered and lyophilized from 0.5 mg/mL in 50mM Phosphate buffer pH-7.4.
Storage Conditions
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated thaw-freeze cycles and store at -80°C. Reconstituted protein can be stored at 4°C for a limited period of time.
Applications Notes
Add 0.2ml of deionized H2O and let the lyophilized pellet dissolve completely.
Amino Acids
GPVYIQYQGF RVQLESMKKL SDLEAQWAPS PRLQAQSLLP AVCHHPALPQ DLQPVCASQE ASSIFKTLRT IANDDCELCV NVACTGCL.

Related Products

CatalogName
32-17659-50Recombinant Human GUCY2C Protein, His Tag
32-17659-100Recombinant Human GUCY2C Protein, His Tag
32-4513-10Recombinant Protein L
32-3516-20CFL2 Recombinant Protein
32-3507-20CENPP Recombinant Protein
32-3506-10CENPM Recombinant Protein
32-3505-20CENPH Recombinant Protein
32-3502-20CEND1 Recombinant Protein
32-3499-20CEACAM21 Recombinant Protein
32-3494-20CDC123 Recombinant Protein

Alternative Products

CatalogName
OPCA04010-1MGGUCA2B Recombinant Protein (Human)
OPCA03867-1MGGUCA2B Recombinant Protein (Mouse)
RP204017GUCA2B Recombinant Protein (Rat)
E51P91179GUCA2B protein, Human, Recombinant (His)
E45M49079M5Guca2b (NM_008191) Mouse Recombinant Protein
TMPY-06353-01GUCA2B Protein, Mouse, Recombinant (His)
PROTQ16661GUCA2B Prouroguanylin Human Recombinant Protein
TP321085MUroguanylin (GUCA2B) (NM_007102) Human Recombinant Protein
OPCA04091-500UGOPCA04091-500UG - GUCA2B Recombinant Protein (Mouse)
TMPH-04489-01GUCA2B Protein, Mouse, Recombinant (Yeast, His)

Popular Products