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Anti-TIMP4 Polyclonal Antibody

CAT: 0793-39-2066-100Size: 100 µg/VialDry Ice: NoHazardous: No
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CAT#:0793-39-2066-100Size:100 µg/Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. And this gene is mapped to chromosome 3p25. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Product Name Alternative
Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4
Gene Name
TIMP4
Gene ID
7079
UniProt
Q99727
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP4 (209-224aa RGHLPLRKEFVDIVQP) .
Target Antigen
Metalloproteinase inhibitor 4
Clonality
Polyclonal
Applications
WB, ELISA
Purification
Immunogen affinity purified.
Format
Lyophilized
Components
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.1-0.5μg/ml; ELISA : 0.1-0.5μg/ml
Isotype
Rabbit IgG

UniProtKB · Q99727

Metalloproteinase inhibitor 4

TIMP4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q99727
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TIMP4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R7K6
Protein keywords

PTM

Disulfide bond

Ligand

Metal-bindingZinc

Molecular function

Metalloenzyme inhibitorMetalloprotease inhibitorProtease inhibitor

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal

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