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Anti-STAT1 Polyclonal Antibody

CAT: 0793-39-2062-100Size: 100 µg/VialDry Ice: NoHazardous: No
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CAT#:0793-39-2062-100Size:100 µg/Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Product Name Alternative
Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; STAT1
Gene Name
STAT1
Gene ID
6772
UniProt
P42224
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human STAT1 (364-378aa FDKDVNERNTVKGFR), different from the related mouse sequence by one amino acid.
Target Antigen
Signal transducer and activator of transcription 1-alpha/beta
Clonality
Polyclonal
Applications
WB
Purification
Immunogen affinity purified.
Components
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.1-0.5μg/ml
Isotype
Rabbit IgG

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