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Anti-CD22 Polyclonal Antibody

CAT: 0793-39-2035-100Size: 100 µg/VialDry Ice: NoHazardous: No
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CAT#:0793-39-2035-100Size:100 µg/Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD22 is a surface glycoprotein of B lymphocytes that is rapidly phosphorylated on cytoplasmic tyrosines after antigen receptor cross-linking. CD22 is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering. The human CD22 gene is expressed specifically in B lymphocytes and likely has an important function in cell-cell interactions. The B cell coreceptor CD22 plays an important role in regulating signal transduction via the B cell Ag receptor.3 CD22 is located within the band region q13.1 of chromosome 19.
Product Name Alternative
B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14; CD22; CD22; SIGLEC2
Gene Name
CD22
Gene ID
933
UniProt
P20273
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CD22 (832-847aa ERPQAQENVDYVILKH) .
Target Antigen
B-cell receptor CD22
Clonality
Polyclonal
Applications
WB, IHC-P
Purification
Immunogen affinity purified.
Format
Lyophilized
Components
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.1-0.5μg/ml; Immunohistochemistry (Paraffin-embedded Section) : 0.5-1μg/ml
Isotype
Rabbit IgG

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