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Polyclonal Antibody to Caveolin-2

CAT: 0793-35-1855-50Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0793-35-1855-50Size:50 μL
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Description
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression.
Product Name Alternative
CAV2
Gene Name
CAV2
Gene ID
858
UniProt
P51636
Host
Rabbit
Reactivity
Human
Immunogen
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Target Antigen
Caveolin-2
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
1.0 mg/mL,100 μl
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 18 22kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · P51636

Caveolin-2

CAV2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51636
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CAV2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A4D0U2, Q9UGM7
Protein keywords

Coding sequence diversity

Alternative initiationAlternative splicing

Cellular component

Cell membraneCytoplasmGolgi apparatusMembraneNucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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