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Polyclonal Antibody to C/EBPbeta

CAT: 0793-35-1843-50Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0793-35-1843-50Size:50 μL
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Description
Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation
Product Name Alternative
IL6DBP|| CRP2|| TCF5|| LAP|| NF-IL6
Gene Name
CEBPB
Gene ID
1051
UniProt
P17676
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.336~340 (E-P-L-L-A) derived from Human C/EBPb.
Target Antigen
C/EBP Beta
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 36kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · P17676

CCAAT/enhancer-binding protein beta

CEBPB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17676
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CEBPB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
C/EBP beta
EC number
—
Processing
—
Secondary accessions
A8K671, Q96IH2, Q9H4Z5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative initiation

Cellular component

CytoplasmNucleus

Biological process

DifferentiationTranscriptionTranscription regulation

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