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Polyclonal Antibody to H2B

CAT: 0793-35-1671-100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0793-35-1671-100Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Product Name Alternative
H2BQ|| GL105|| H2B.1|| H2BFQ|| H2BGL105
Gene Name
HIST1H2BB
Gene ID
3018
UniProt
P33778
Host
Rabbit
Reactivity
Rat, Mouse, Human
Immunogen
Peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.
Target Antigen
H2B
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 14kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · P33778

Histone H2B type 1-B

H2B1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P33778
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
H2BC3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q4KN36
Protein keywords

Technical term

3D-structureReference proteome

PTM

AcetylationADP-ribosylationGlycoproteinHydroxylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Cellular component

ChromosomeNucleosome coreNucleus

Molecular function

DNA-binding

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