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Anti-Human CD35 APC (Clone : E11)

CAT: 0793-30-2576-100Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0793-30-2576-100Size:100 Tests
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Description
CD35 (complement receptor 1, CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes, monocytes, erythrocytes, B cells and folicular dendritic cells. Besides its role in complement cascade, CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.Specificity : The mouse monoclonal antibody E11 recognizes an extracellular epitope of CD35 (CR1), a type I transmembrane glycoprotein expressed on granulocytes, monocytes, B cells, folicular dendritic cells, erythrocytes, NK and T cell subsets, as well as e.g. on glomerulal podocytes.
Product Name Alternative
CR1, KN, C3BR, C4BR, complement C3b/C4b receptor 1 (Knops blood group)
Gene Name
CR1
Gene ID
1378
Reactivity
Human
Immunogen
Acute monocytic leukemia cells and normal blood monocytes
Target Antigen
CD35
Clonality
Monoclonal
Clone
E11
Applications
FACS
Purification
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Components
Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Applications Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Isotype
Mouse IgG1
Conjugate
APC

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Alternative Products

CatalogName
AMM02165GMonoclonal CR1 / CD35 Antibody (clone E11), Clone: E11
HB625107Anti-Human CD35/CR1 Antibody (E11)
FCE1997-01PE Anti-Human CD35 Antibody[E11]
FCE1994-01Purified Anti-Human CD35 Antibody[E11]
E-AB-F1062B-01Biotin Anti-Human CD35 Antibody[E11]
E-AB-F1062C-01FITC Anti-Human CD35 Antibody[E11]
E-AB-F1062E-01APC Anti-Human CD35 Antibody[E11]
APC-30214-01APC Anti-Human CD35 Antibody (E11)
PE-30214-01PE Anti-Human CD35 Antibody (E11)
FITC-30214-01FITC Anti-Human CD35 Antibody (E11)

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