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(-) -Fucose

CAT: 0804-HY-N1480-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1480-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-) -Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth[2].
CAS Number
2438-80-4
Product Name Alternative
6-Desoxygalactose; L- (-) -Fucose; L-Galactomethylose
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection; Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/_-_-Fucose.html
Concentration
10mM
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C[C@H]([C@@H]([C@@H]([C@H](C)O)O)O)O
Molecular Formula
C6H12O5
Molecular Weight
164.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Becker DJ, et al. Fucose: biosynthesis and biological function in mammals. Glycobiology. 2003 Jul;13 (7) :41R-53R.|[2]Howard MC, et al., l-Fucose prevention of renal ischaemia/reperfusion injury in Mice. FASEB J. 2020 Jan;34 (1) :822-834.|[3]Tomsik, P, et al., L-rhamnose and L-fucose suppress cancer growth in mice.cent.eur.j.biol.6, 1–9 (2011) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
Human Endogenous Metabolite