(-) -Fucose

• Description:

  (-) -Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-) -Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth[2].

• Product Name Alternative:

  6-Desoxygalactose; L- (-) -Fucose; L-Galactomethylose

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Metabolic Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/_-_-Fucose.html

• Concentration:

  10mM

• Purity:

  99.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O=C[C@H]([C@@H]([C@@H]([C@H](C)O)O)O)O

• Molecular Formula:

  C6H12O5

• Molecular Weight:

  164.16

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Becker DJ, et al. Fucose: biosynthesis and biological function in mammals. Glycobiology. 2003 Jul;13 (7) :41R-53R.|[2]Howard MC, et al., l-Fucose prevention of renal ischaemia/reperfusion injury in Mice. FASEB J. 2020 Jan;34 (1) :822-834.|[3]Tomsik, P, et al., L-rhamnose and L-fucose suppress cancer growth in mice.cent.eur.j.biol.6, 1–9 (2011) .

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen)

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 2

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [2438-80-4]