GCN2-IN-1

GCN2-IN-1

• CAS Number: 1448693-69-3
• UNSPSC Description: GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of IC50 of 0.3-3 μM in the cell assay[1].
• Target Antigen: Eukaryotic Initiation Factor (eIF)
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/GCN2-IN-1.html
• Purity: 98.0
• Solubility: DMSO : 60 mg/mL (ultrasonic;warming)
• Smiles: C1(NC2=CN(C3CCOCC3)N=C2)=NC=C(N=NN4C5=CC6=C(C=C5)C=NN6)C4=N1
• Molecular Weight: 402.41
• References & Citations: [1]Dieter Dorsch, et al. Triazolo[4,5-d]pyrimidine derivatives. WO2013110309A1.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported