PPARGC1A antibody

• Background:

  PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM(RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.

• Synonyms:

  Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha)|Ligand effect modulator 6|PPARGC1A|LEM6|PGC1|PGC1A|PPARGC1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

• Target:

  PPARGC1A

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:2000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4