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BMS270394

CAT: 0804-HY-114071-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114071-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS270394 is a nuclear retinoic acid receptor (RAR-γ) agonist with the EC50 values of 30 nM and 400 nM for humanRAR-γ and RAR-β, respectively[1].
CAS Number
262433-54-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms270394.html
Purity
98.0
Smiles
CC1(C2=CC([C@@H](O)C(NC3=C(C=C(C=C3)C(O)=O)F)=O)=CC=C2C(C)(CC1)C)C
Molecular Formula
C23H26FNO4
Molecular Weight
399.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Klaholz BP, et al. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc Natl Acad Sci U S A. 2000;97 (12) :6322-6327.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RXRβ; RXRγ

Alternative Products

CatalogName
GTR19198049BMS270394

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