Bis-PEG4-TFP ester

• Description:

  Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bis-peg4-tfp-ester.html

• Purity:

  98.45

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CCOCCOCCOCCOCCC(OC1=C(C(F)=CC(F)=C1F)F)=O)OC2=C(C(F)=CC(F)=C2F)F

• Molecular Formula:

  C24H22F8O8

• Molecular Weight:

  590.41

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  1446282-42-3