4-Methylcatechol-d8

4-Methylcatechol-d8

• CAS Number: 1219803-18-5
• UNSPSC Description: 4-Methylcatechol-d8 is the deuterium labeled 4-Methylcatechol[1]. 4-Methylcatechol, a metabolite of p-toluate, is a substrate as well as a suicide inhibitor of Catechol 2,3-Dioxygenase[2].
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Solubility: 10 mM in DMSO
• Smiles: [2H]OC(C([2H])=C([2H])C(C([2H])([2H])[2H])=C1[2H])=C1O[2H]
• Molecular Weight: 132.19
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Okuta A, et al. Construction of chimeric catechol 2,3-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70(3):1804-10.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported