4-Methylcatechol-d8

• Description :

  4-Methylcatechol-d8 is the deuterium labeled 4-Methylcatechol[1]. 4-Methylcatechol, a metabolite of p-toluate, is a substrate as well as a suicide inhibitor of Catechol 2,3-Dioxygenase[2].

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Solubility :

  10 mM in DMSO

• Smiles :

  [2H]OC(C([2H])=C([2H])C(C([2H])([2H])[2H])=C1[2H])=C1O[2H]

• Molecular Formula :

  C7D8O2

• Molecular Weight :

  132.19

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Okuta A, et al. Construction of chimeric catechol 2,3-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70 (3) :1804-10.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1219803-18-5]