A-967079

CAT: 0804-HY-108463-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-108463-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS.

CAS Number

1170613-55-4

UNSPSC

12352005

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/A-967079.html

Purity

99.30

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCC(/C(C)=C/C1=CC=C(F)C=C1)=N\O

Molecular Formula

C12H14FNO

Molecular Weight

207.24

References & Citations

[1]McGaraughty S, et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Mol Pain. 2010 Mar 5;6:14.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Alternative Products

Catalog	Name
B7702-10	A 967079
GTR19167776-01	A-967079

A-967079

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