HEK293/Human GPR75 Stable Cell Line
CAT:
716-CHEK-ATP174-2Vials
Size:
2 Vials
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
HEK293/Human GPR75 Stable Cell Line
- Background: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
- Description: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
- Host: HEK 293
- Origin Species: Human
- Target: GPR75
- Applications: Useful for cell-based GPR75 binding assay
- Format: Liquid
- Shipping Conditions: Dry ice
- Storage Conditions: Frozen in liquid nitrogen