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CSF1R/CD115 Protein (Human)

CAT: 1543-P514510Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P514510Size:100 µg
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Abbreviation
CSF1R/CD115
Synonyms
C-FMS, CD115, CSF-1 receptor, CSF-1-R, CSF-1R, CSF1R, FIM2, FMS, HDLS, M-CSF-R, MCSF Receptor , Macrophage colony-stimulating factor 1 receptor, Proto-oncogene c-Fms
UniProt
P07333
Host
HEK 293
Applications
Cell culture, ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
1. Immobilized sMCSFR at 10 μg/ml (100 μl/well) can bind biotinylated human CSF1-His, The EC50 of biotinylated human CSF1-His is 32-74. 8 ng/ml. 2. Measured by its ability to inhibit the human CSF-induced proliferation of M‐NFS‐60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.3-1. 5 μg/mL in the presence of 3 ng/mL of rhM-CSF.
Function
Met 1-Glu 512
Molecular Weight
55.1 kDa
Species
Human

UniProtKB · P07333

Macrophage colony-stimulating factor 1 receptor

CSF1R_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P07333
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CSF1R
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B5A955, D3DQG2, Q6LDW5, Q6LDY4, Q86VW7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneMembrane

Disease

Disease variantNeurodegenerationProto-oncogene

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Biological process

ImmunityInflammatory responseInnate immunity

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

KinaseReceptorTransferaseTyrosine-protein kinase

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Alternative Products

CatalogName
PX-P6053-100Human CD115 / CSF1R recombinant protein
PPT-11104Human CD115/CSF1R Recombinant Protein
PKSH031818Recombinant Human CSF1R/CD115 Protein
ARO-P14629Recombinant Human CD115/CSF1R Protein, N-His
ARO-P18169-01Human CD115/CSF1R Recombinant Protein, C-Fc
bs-100572P-01Recombinant Human CD115/CSF1R Protein, C-His
KMH290Recombinant Human CD115/CSF1R Protein, His Tag
GTR19145476-01Recombinant Human CD115/CSF1R Protein, C-Fc
MBS2546470-01Recombinant Human CSF1R / MCSF Receptor / CD115 Protein
PKSH032726-01Recombinant Human CSF1R/CD115 Protein (Fc Tag)

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