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Protein (C-mFc, SARS-CoV-2)

CAT: 1543-P512684Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P512684Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Synonyms
SARS-CoV-2 RBD Protein, SARS-CoV-2 Spike RBD Protein
UniProt
P0DTC2
Host
HEK 293
Tag
C-mFc
Applications
ELISA
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
1. Immobilized 2019-nCoV S Protein RBD-mFc V2 (PKSV030307) at 5μg/ml (100 μl/well) can bind Human ACE-2-Fc (PKSR030492) . The ED50 of Recombinant Human ACE-2-Fc (PKSR030492) is 5-50 ng/ml, 2. Immobilized RBD-mFc V2 (PKSV030307) at 5μg/ml (100 μl/well) can bind Anti-2019-nCoV S1 mAb (5D9) . The ED50 of Anti-2019-nCoV S1 mAb (5D9) is 5-30 ng/ml.
Function
Arg319-Phe541
Molecular Weight
51.5 kDa
Species
SARS-CoV-2

UniProtKB · P0DTC2

Spike glycoprotein

SPIKE_SARS2 · Severe acute respiratory syndrome coronavirus 2

View on UniProt ↗
Primary accession
P0DTC2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
S
Protein existence
1: Evidence at protein level
Organism
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Taxonomy ID
2697049
Alternative names
S glycoprotein
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Domain

Coiled coilSignalTransmembraneTransmembrane helix

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Biological process

Fusion of virus membrane with host endosomal membraneFusion of virus membrane with host membraneHost-virus interactionInhibition of host innate immune response by virusInhibition of host tetherin by virusViral attachment to host cellViral immunoevasionViral penetration into host cytoplasmVirulenceVirus entry into host cell

Cellular component

Host cell membraneHost membraneMembraneViral envelope proteinVirion

Molecular function

Superantigen

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