DLL4 Protein (C-hFc, Human)

CAT: 1543-P514785Size: 100 µgDry Ice: NoHazardous: No

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CAT#:1543-P514785Size:100 µg

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Abbreviation

DLL4

Synonyms

DLL4, Delta-like protein 4, Delta4, Drosophila Delta homolog 4

UniProt

Q9NR61

Host

HEK 293

Tag

C-hFc

Applications

Cell culture, ELISA

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

1. Immobilized human DLL4 at 10 μg/mL (100 μL/well) can bind biotinylated mouse NOTCH1-his. The EC50 of biotinylated mouse NOTCH1-his is 40 ng/mL. 2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 1-8 μg/mL in the presence of 500 ng/mL recombinant human BMP2.

Function

Met 1-Pro 524

Molecular Weight

81.0 kDa

Species

Human

UniProtKB · Q9NR61

Delta-like protein 4

DLL4_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9NR61
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: DLL4
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: Q3KP23, Q9NQT9

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

AngiogenesisDifferentiationNeurogenesisNotch signaling pathwaySensory transductionVision

Cellular component

Cell membraneMembrane

Molecular function

Developmental protein

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

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Alternative Products

Catalog	Name
E51P01958	DLL4 Protein, Human, Recombinant (C-hFc)
TMPY-00776-01	DLL4 Protein, Human, Recombinant (hFc)
Z03955-500	DLL4 hFc Chimera, Human
TMPY-00776U-01	DLL4 Protein, Human, Recombinant (hFc) V2
E45H50250M4-50	DLL4 Protein, Human, Recombinant (ECD, hFc Tag)
CD01911-01	Recombinant Human DLL4 protein (C-10His)
COV442-01	Recombinant Human DLL4 Protein, C-Fc
PR17054	Recombinant Human DLL4 Protein, C-His
E51P00104	DLL4 Protein, Human, Recombinant (C-His)
GTR18905550-01	Human DLL4 protein