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MAC13772

CAT: 0804-HY-116872-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-116872-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound[1].
CAS Number
4871-40-3
Product Name Alternative
Ro 40-7591-d4, Trimethoprim 1-N-oxide, Trimethoprim 3-N-oxide
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mac13772.html
Purity
99.33
Solubility
DMSO : 17.86 mg/mL (ultrasonic)
Smiles
O=C(NN)CSC1=CC=CC=C1[N+]([O-])=O
Molecular Formula
C8H9N3O3S
Molecular Weight
227.24
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Zlitni S, et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9 (12) :796-804.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5753448MAC13772
A18788-50MAC13772 50mg
A18788-25MAC13772 25mg
A18788-10MAC13772 10mg
A18788-100MAC13772 100mg
A18788-5MAC13772 5mg
A18788-10mM-DMAC13772 10mM * 1mL in DMSO

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