Products for Research Use Only

Claudin 5 Rabbit Polyclonal Antibody

CAT: 0013-GTR17705762-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17705762-01Size:50 μL
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Description
Claudin 5 Rabbit Polyclonal Antibody
Product Name Alternative
AWAL; BEC1; CPETRL1; TMDVCF; TMVCF; MBEC1; CLD5_BOVIN; CLDN5; CLD5_HUMAN; Transmembrane protein deleted in VCFS (TMDVCF) ; CLD5_MOUSE; Brain endothelial cell clone 1 protein; Lung-specific membrane protein; claudin 5; transmembrane protein deleted in velocardiofacial syndrome
UniProt
O00501
Reactivity
Human, Mouse
Immunogen
KLH conjugated synthetic peptide derived from human Claudin 5 (29-81/218aa)
Target
CLDN5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=2ug/Test
Form
Liquid
Molecular Weight
23 kDa
References & Citations
Maysam Havasi Mehr 1, Shahein Momenabadi 2, Ali Vakili 3, Abbas Pakdel 4, Abbas Ali Vafaei 5, Abedin Vakili Neuroprotective effects of Daphnetin on hippocampal neurons and blood-brain barrier integrity in a mouse model of cerebral ischemia Brain Res Bull ., (2024), Maydelín Espadín a b , Miguel Cervantes c , Angélica Coyoy-Salgado d , Claudia Espinosa-Garcia e , Beatriz Gómez-González b , Gabriela Moralí Progesterone restores blood-brain barrier and memory after chronic cerebral hypoperfusion in male rats Brain Behavior and Immunity Integrative, (2025), Yuanyuan Bai 1 2, Haiyan Wu 1 3, Xu Wang 4, Yang Guo 1 2, Bingqing Gong 1 2, Beibei Dong 2, Yonghao Yu A mitochondrial-derived peptide MOTS-c contributes to the protective effect against brain injury associated with LPS-induced sepsis by strengthening the blood-brain barrier's ultrastructure Int J Neurosci, (2025), Jessica J Avilez-Avilez 1 2, Jesús Enrique García-Aviles # 1 3, Ricardo Jair Ramírez-Carreto # 4 5, Verónica Salas-Venegas 4 6, Mara A Guzmán-Ruiz 3, Fernanda Medina-Flores 7, Mina Königsberg 8, Anahí Chavarría 9, Beatriz Gómez-González Progressive Blood-Brain Barrier Disruption in Sleep-Restricted Young Mice: Cellular Senescence and Neuroinflammation Crosstalk Neurochem Res ., (2025)
Pubmed id
39447767, 40753494, 40824389
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
A customer has reported negative results in live-cell applications for FACS, indicating that a fixation step may be required.
Prediction Reactivity
Bovine, Equine, Porcine, Rabbit, Rat, Sheep
Tested Applications
FC, IF, IHC-Fr, IHC-P, WB
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

UniProtKB · O00501

Claudin-5

CLD5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00501
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CLDN5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KS11, Q53XW2, Q8WUW3
Protein keywords

Cellular component

Cell junctionCell membraneMembraneTight junction

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix