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Abatacept Biosimilar - Research Grade

CAT: 1148-ICH5185-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1148-ICH5185-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Recombinant protein composed of the extracellular domain of CTLA-4 fused with the Fc region of human immunoglobulin gamma 1 (hIgG1) . Abatacept binds to CD80 (B7-1) with more avidity than to CD86 (B7-2) .
Host
CHO Cells
Reactivity
Human
Target
CTLA-4 Fc Fusion Protein
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This fusion protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Specificity
Fusion protein of a Fc fragment (human IgG1 isotype) and the extracellular domain of CTLA-4
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

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