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Lemzoparlimab Biosimilar - Research Grade

CAT: 1148-ICH5034-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1148-ICH5034-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
CD47, IAP, MER6, OA3, CD47 molecule, integrin associated protein
UniProt
Q08722
Reactivity
Human
Target
CD47
Isotype
IgG1
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Specificity
Detects human CD47. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Lemzoparlimab.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

UniProtKB · Q08722

Leukocyte surface antigen CD47

CD47_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q08722
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD47
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K198, D3DN59, Q53Y71, Q96A60
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisApoptosisCell adhesionInflammatory response

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoproteinPyrrolidone carboxylic acid

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

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