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Human K-RAS Recombinant Protein

CAT: 0519-PROTP01116-20ugSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0519-PROTP01116-20ugSize:20 µg
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Description
Human K-RAS Recombinant Protein expressed in E. coli with His-tag. Sequence domain: 1-185aa (partial) . Application (s) : SDS-PAGE.
Synonyms
GTPase Kras, KRAS proto-oncogene GTPase, KRAS2, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral oncogene homolog, KRAS1, K-Ras4B, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, RASK2
Gene Name
KRAS
UniProt
P01116
Tag
His-Tag
Source
E. coli
Applications
SDS-PAGE
Field of Research
Cancer
Purification
> 90% by SDS-PAGE
Concentration
0.5mg/mL (determined by Bradford assay)
Form
Liquid
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long-term storage, aliquot and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. (Ships with gel ice.)
Observed Molecular Weight
23.2 kDa (205aa) confirmed by MALDI-TOF
Contents
20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl,1mM DTT, 10% glycerol

UniProtKB · P01116

GTPase KRas

RASK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01116
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KRAS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.5.2
Processing
Precursor
Secondary accessions
A8K8Z5, B0LPF9, P01118, Q96D10
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondLipoproteinMethylationPalmitatePrenylationUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

CardiomyopathyDeafnessDisease variantEctodermal dysplasiaIntellectual disabilityProto-oncogene

Cellular component

Cell membraneCytoplasmMembrane

Ligand

GTP-bindingNucleotide-binding

Molecular function

Hydrolase