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Anti-PCBD1 Antibody

CAT: 0519-A07264Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07264Size:100 µL
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Description
Boster Bio Anti-PCBD1 Antibody catalog # A07264. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Pterin-4-alpha-carbinolamine dehydratase; PHS;4.2.1.96;4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; PCBD1; DCOH, PCBD
Gene Name
PCBD1
UniProt
P61457
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PCBD1 (NP_000272.1) .
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
12000 MW
Gene Name Synonym
Pterin-4-alpha-carbinolamine dehydratase
Subcellular Location
Cytoplasm. Nucleus. Cytoplasmic and/or nuclear.
Protein Name
Pterin-4-alpha-carbinolamine dehydratase
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

UniProtKB · P61457

Pterin-4-alpha-carbinolamine dehydratase

PHS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61457
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PCBD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PHS
EC number
4.2.1.96
Processing
—
Secondary accessions
P70519, P80095, Q9D930
Protein keywords

PTM

Acetylation

Molecular function

ActivatorLyase

Cellular component

CytoplasmNucleus

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variant

Biological process

Tetrahydrobiopterin biosynthesisTranscriptionTranscription regulation

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