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Anti-CLEC2D Antibody

CAT: 0519-A06635-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06635-1Size:100 µL
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Background
CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts (PMID: 21930700; 14753741) . Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs (PMID: 21930700) . CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and their interaction differentially regulates NK- and T-cell functions (PMID: 16339513, 16339512) . It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells (PMID:14753741; 20415786) .
Description
Boster Bio Anti-CLEC2D Antibody catalog # A06635-1. Tested in WB, ELISA applications. This antibody reacts with Human.
Gene Name
CLEC2D
UniProt
Q9UHP7
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human CLEC2D recombinant protein (Position: D3-W151) .
Clonality
Polyclonal
Applications
WB, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

UniProtKB · Q9UHP7

C-type lectin domain family 2 member D

CLC2D_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UHP7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CLEC2D
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D6CI39, D6CI40, D6CI41, Q6YID5, Q8WUP7, Q9HD37, Q9HD38
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndoplasmic reticulumMembrane

PTM

Disulfide bondGlycoprotein

Ligand

Lectin

Molecular function

Receptor

Domain

Signal-anchorTransmembraneTransmembrane helix

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PAab01751Anti-CLEC2D antibody
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