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Anti-EIF4G3 Antibody

CAT: 0519-A06598-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06598-1Size:100 µL
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Background
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
Description
Boster Bio Anti-EIF4G3 Antibody catalog # A06598-1. Tested in WB, IHC, ICC/IF, IP, ELISA applications. This antibody reacts with Human.
Gene Name
EIF4G3
UniProt
O43432
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human EIF4G3 recombinant protein (Position: 199-512) .
Clonality
Polyclonal
Applications
WB, IHC, ICC/IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

UniProtKB · O43432

Eukaryotic translation initiation factor 4 gamma 3

IF4G3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43432
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EIF4G3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
eIF-4-gamma 3, eIF-4G 3, eIF4G 3
EC number
—
Processing
—
Secondary accessions
B9EGQ7, Q15597, Q504Z1, Q5SWC3, Q8NEN1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilRepeat

Molecular function

Initiation factorRNA-binding

PTM

Phosphoprotein

Biological process

Protein biosynthesisTranslation regulation

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