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Anti-CDK10 (E63) Antibody

CAT: 0519-A06507Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06507Size:100 µL
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Description
Boster Bio Anti-CDK10 (E63) Antibody catalog # A06507. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Cyclin-dependent kinase 10;2.7.11.22; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10
Gene Name
CDK10
UniProt
Q15131
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 30-84 of Human Cdk10.
Clonality
Polyclonal
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572) . Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling (PubMed:27104747) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
41038 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Cyclin-dependent kinase 10
Subcellular Location
Cytoplasm, cytoskeleton, cilium basal body
Protein Name
Cyclin-dependent kinase 10
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

UniProtKB · Q15131

Cyclin-dependent kinase 10

CDK10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15131
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CDK10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.22
Processing
—
Secondary accessions
A8K370, A8K8I6, A8MXU6, B3KQJ3, B7Z420, D3DX82, D3DX83, Q0VGZ7, Q15130, Q6PJC0
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell projectionCytoplasmCytoskeleton

Biological process

Cilium biogenesis/degradation

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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