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Anti-RECK Antibody

CAT: 0519-A06439Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A06439Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-RECK Antibody (Catalog# A06439) . Tested in IHC, ICC, IF, WB, ELISA applications. This antibody reacts with Human, Mouse.
Synonyms
RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein
Gene Name
RECK
UniProt
O95980
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A peptide derived from human RECK. Immunogen sequence location: 21-70
Clonality
Polyclonal
Tissue Specificity
Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.
Applications
IHC, ICC, IF, WB, ELISA
Field of Research
Cancer, Cell Biology, Oncoproteins/Suppressors, Protease Inhibitors, Proteolysis/Ubiquitin, Tumor Suppressors
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Function
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Storage Conditions
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
106457 MW
Gene Name Synonym
Reversion-inducing cysteine-rich protein with Kazal motifs
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Isotype
Rabbit IgG
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

UniProtKB · O95980

Reversion-inducing cysteine-rich protein with Kazal motifs

RECK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95980
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RECK
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hRECK
EC number
—
Processing
Precursor
Secondary accessions
B2RNS1, Q5W0K6, Q8WX37
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinGPI-anchorLipoprotein

Molecular function

Protease inhibitorSerine protease inhibitor

Domain

RepeatSignal

Disease

Tumor suppressor

Biological process

Wnt signaling pathway

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