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Anti-AARS Antibody

CAT: 0519-A03935Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A03935Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-AARS Antibody catalog # A03935. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Alanine--tRNA ligase, cytoplasmic
Gene Name
AARS
UniProt
P49588
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human AARS (NP_001596.2) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Catalyzes the attachment of alanine to tRNA (Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA (Ala) (PubMed:27622773, PubMed:27911835, PubMed:28493438) . Also edits incorrectly charged tRNA (Ala) via its editing domain (PubMed:27622773, PubMed:27911835, PubMed:28493438) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
106810 MW
Gene Name Synonym
Alanine--tRNA ligase, cytoplasmic
Subcellular Location
Cytoplasm
Protein Name
Alanine--tRNA ligase, cytoplasmic
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

UniProtKB · P49588

Alanine--tRNA ligase, cytoplasmic

SYAC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49588
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AARS1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
6.1.1.7
Processing
—
Secondary accessions
A6NF14, B4DR45, Q53GV7, Q96FA0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

Aminoacyl-tRNA synthetaseLigaseRNA-bindingtRNA-binding

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

Charcot-Marie-Tooth diseaseDisease variantEpilepsyNeurodegenerationNeuropathy

Cellular component

CytoplasmNucleus

Biological process

Protein biosynthesis

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