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Anti-LRRC8A Antibody

CAT: 0519-A03517-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A03517-1Size:100 µL
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Background
LRRC8A, also named as SWELL1, KIAA1437 and LRRC8, belongs to the LRRC8 family. LRRC8A is a ubiquitous and integral component of the VRAC and has been reported to be required for regulation of cell volume. It indicates that LRRC8A plays a role in regulating the flow of ions, especially anions, into and out of cells (PMID: 32079488) . Additionally, there have been several reports that LRRC8A is critical for differentiation of adipocytes and lymphocytes (PMID: 31323188) . The molecular weight of LRRC8A is 94 kDa.
Description
Boster Bio Anti-LRRC8A Antibody catalog # A03517-1. Tested in WB, IHC, IP, ELISA. This antibody reacts with Human, Mouse, Rat.
Gene Name
LRRC8A
UniProt
Q8IWT6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human LRRC8A recombinant protein (Position: A466-K807) .
Clonality
Polyclonal
Applications
WB, IHC, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

UniProtKB · Q8IWT6

Volume-regulated anion channel subunit LRRC8A

LRC8A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8IWT6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRRC8A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q6UXM2, Q8NCI0, Q9P2B1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinPhosphoprotein

Cellular component

Cell membraneLysosomeMembrane

Coding sequence diversity

Chromosomal rearrangement

Biological process

DifferentiationIon transportSpermatogenesisTransport

Molecular function

Ion channel

Domain

Leucine-rich repeatRepeatTransmembraneTransmembrane helix

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