Anti-ABCB5 Antibody

CAT: 0519-A02979Size: 100 µgDry Ice: YesHazardous: No

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CAT#:0519-A02979Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Anti-ABCB5 Antibody is a ATP-Binding Cassette protein. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5. ABCB5 antibody is ideal for Cancer and Signal Transduction research.

Description

Boster Bio Anti-ABCB5 Antibody (Catalog # A02979) . Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Synonyms

ABCB5, ABCB 5, ABCB-5, ATP binding cassette sub family B (MDR/TAP) member 5, ATP binding cassette sub family B member 5, EST422562, P glycoprotein ABCB5

Gene Name

ABCB5

UniProt

Q2M3G0

Host

Rabbit

Reactivity

Human

Immunogen

ABCB5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues corresponding to an internal region of human ABCB5.

Clonality

Polyclonal

Applications

ELISA, IHC, WB

Field of Research

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific for human ABCB5 protein. A BLAST analysis was used to suggest partial cross-reactivity with ABCB5 from monkey (85% homology), rat (68% homology) and mouse (62% homology) sources. Cross-reactivity with ABCB5 from other sources has not been determined.

Concentration

1.1 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Shipping Conditions

Dry Ice Shipping

Storage Conditions

Store Anti-ABCB5 at -20°C prior to opening. Aliquot antibody and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening. (Ship on dry ice.)

Isotype

IgG

Contents

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

UniProtKB · Q2M3G0

ATP-binding cassette sub-family B member 5

ABCB5_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q2M3G0
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ABCB5
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A4D131, A7BKA4, B5MD19, B7WPL1, F8QQP8, F8QQP9, J3KQ04, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1

Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneMembrane

Biological process

DifferentiationTransport

PTM

Glycoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatTransmembraneTransmembrane helix

Molecular function

Translocase

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