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Anti-CDCP1 Antibody

CAT: 0519-A02411Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A02411Size:100 µL
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Description
Boster Bio Anti-CDCP1 Antibody catalog # A02411. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
CUB domain-containing protein 1; Membrane glycoprotein gp140; Subtractive immunization M plus HEp3-associated 135 kDa protein; SIMA135; Transmembrane and associated with src kinases; CD318; CDCP1; TRASK; UNQ2486/PRO5773
Gene Name
CDCP1
UniProt
Q9H5V8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CDCP1. AA range:241-290
Clonality
Polyclonal
Tissue Specificity
Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
Applications
WB, IHC, IF, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/mL
Form
Liquid
Function
May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
92932 MW
Gene Name Synonym
CUB domain-containing protein 1
Subcellular Location
Isoform 1: Cell membrane ; Single-pass membrane protein . Shedding may also lead to a soluble peptide.
Protein Name
CUB domain-containing protein 1
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

UniProtKB · Q9H5V8

CUB domain-containing protein 1

CDCP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H5V8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CDCP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

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