Anti-ACE2 Antibody

CAT: 0519-A00756Size: 0.1 mgDry Ice: NoHazardous: No

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CAT#:0519-A00756Size:0.1 mg

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Background

COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans

Description

Boster Bio Anti-ACE2 Antibody (Catalog # A00756) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Synonyms

ACEH, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, ACEH, SARS-CoV receptor, SARS-CoV-2 receptor

Gene Name

ACE2

UniProt

Q9BYF1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

Anti-ACE2 has no cross response to ACE1.

Immunogen

Anti-ACE2 antibody was raised against a peptide corresponding to 17 amino acids near the center of human ACE2. The immunogen is located within amino acids 180 - 230 of ACE2.

Clonality

Polyclonal

Tissue Specificity

Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) . Expressed in heart, kidney, testis, and gastrointestinal system.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Infectious Diseases

Purification

ACE2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function.

Storage Conditions

ACE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

92463 MW

Gene Name Synonym

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Subcellular Location

Processed angiotensin-converting enzyme 2: Secreted.

Prediction Reactivity

Bovine

Protein Name

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Isotype

IgG

Contents

ACE2 Antibody is supplied in PBS containing 0.02% sodium azide.

UniProtKB · Q9BYF1

Angiotensin-converting enzyme 2

ACE2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9BYF1
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ACE2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.17.23
Processing: Precursor
Secondary accessions: A0A7D6JAD5, C7ECU1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

CarboxypeptidaseHost cell receptor for virus entryHydrolaseMetalloproteaseProteaseReceptor

Cellular component

Cell membraneCell projectionCytoplasmMembraneSecreted

Ligand

ChlorideMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Biological process

Host-virus interaction

Domain

SignalTransmembraneTransmembrane helix

Related Products

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M00756-2-20μl	Anti-ACE2 Rabbit Monoclonal Antibody
M00756-2-200μl	Anti-ACE2 Rabbit Monoclonal Antibody
M00756-carrier-free	Anti-ACE2 Rabbit Monoclonal Antibody, Carrier-free
EK1188	Mouse ACE2 ELISA Kit PicoKine®
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A00251-2	Anti-ACE1 Antibody

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A2072-100	Anti-ACE2 Antibody
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T9901A-677-01	Anti-ACE2 Antibody (1Y227)
TMAY-00276-01	Anti-ACE2 Antibody (1T578)
MBS1569174-01	Anti-Human ACE2 Antibody
SLM-51221M-01	Mouse Anti-ACE2 antibody
PHJ51601	Anti-ACE2 Polyclonal Antibody
SL23443R-01	Rabbit Anti-ACE2 antibody
T9901A-678-01	Anti-ACE2 Antibody (7D640)
TMAY-03714-01	Anti-ACE2 Antibody (4J88)