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Anti-EZH2 Antibody

CAT: 0519-A00050-3-400ulSize: 400 µLDry Ice: NoHazardous: No
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CAT#:0519-A00050-3-400ulSize:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EZH2 is a protein that transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin.
Description
Boster Bio Anti-EZH2 Antibody (Catalog # A00050-3) . Tested in WB, IHC-P, IF, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.
Synonyms
Histone-lysine N-methyltransferase EZH2, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, EZH2, KMT6
Gene Name
EZH2
UniProt
Q15910
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This EZH2 antibody is generated from rabbits immunized with a recombinant fragment (N-term) protein from human EZH2.
Clonality
Polyclonal
Tissue Specificity
In the ovary, expressed in primordial follicles and oocytes and also in external follicle cells (at protein level) (PubMed:31451685) . Expressed in many tissues (PubMed:14532106) Overexpressed in numerous tumor types including carcinomas of the breast, colon, larynx, lymphoma and testis (PubMed:14532106)
Applications
WB, IHC-P, IF, Flow Cytometry
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
2232359930923826
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
85363 Da
Subcellular Location
Nucleus. Note=Localizes to the inactive X chromosome in trophoblast stem cells. {ECO:0000250|UniProtKB:Q61188}
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

UniProtKB · Q15910

Histone-lysine N-methyltransferase EZH2

EZH2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15910
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EZH2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.356
Processing
—
Secondary accessions
B2RAQ1, B3KS30, B7Z1D6, B7Z7L6, Q15755, Q75MG3, Q92857, Q96FI6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsTranscriptionTranscription regulation

Molecular function

Chromatin regulatorMethyltransferaseRepressorTransferase

Disease

Disease variant

PTM

GlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Ligand

S-adenosyl-L-methionine