DMT-2'O-Methyl-rU Phosphoramidite

DMT-2'O-Methyl-rU Phosphoramidite

• CAS Number: 110764-79-9
• UNSPSC Description: DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis[1][2].
• Target Antigen: DNA/RNA Synthesis
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dmt-2-o-methyl-ru-phosphoramidite.html
• Purity: 99.15
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OC)[C@H](N5C(NC(C=C5)=O)=O)O4
• Molecular Weight: 760.81
• References & Citations: [1]Stump MD, et al. The use of modified primers to eliminate cycle sequencing artifacts. Nucleic Acids Res. 1999 Dec 1;27(23):4642-8.|[2]Takahashi M, et al. Synthesis and characterization of 2'-modified-4'-thioRNA: a comprehensive comparison of nuclease stability. Nucleic Acids Res. 2009 Mar;37(4):1353-62.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported