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Anti-Complement C3 Monoclonal Antibody

CAT: 0519-M00168-2Size: 100 µL/VialDry Ice: NoHazardous: No
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CAT#:0519-M00168-2Size:100 µL/Vial
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-Complement C3 Monoclonal Antibody catalog # M00168-2. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.
Synonyms
Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3 beta chain; C3-beta-c; C3bc; Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein; ASP; C3adesArg; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2; C3; CPAMD1
Gene Name
C3
Gene ID
718
UniProt
P01024
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human C3 / C3a
Clonality
Monoclonal
Clone
Clone: AEIC-3
Tissue Specificity
Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods. .
Applications
WB, ICC, IF, Flow Cytometry
Field of Research
Apoptosis, Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling, Intracellular, Oncoproteins/Suppressors, p53 Pathway, Transcription, Tumor Suppressors
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
187148 MW
Observed Molecular Weight
30 kDa
Gene Name Synonym
Complement C3
Subcellular Location
Secreted.
Protein Name
P2X purinoceptor 1
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

UniProtKB · P01024

Complement C3

CO3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01024
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
C3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A7E236
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Age-related macular degenerationDisease variantHemolytic uremic syndrome

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinThioester bond

Biological process

Complement alternate pathwayComplement pathwayFatty acid metabolismImmunityInflammatory responseInnate immunityLipid metabolism

Cellular component

Secreted

Domain

Signal

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