Products for Research Use Only
RegisterLogin

Anti-E2F3 Antibody Picoband®

CAT: 0519-A03068-2Size: 100 µg/VialDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-A03068-2Size:100 µg/Vial
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Transcription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3. The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions. This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts ly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle.
Description
Boster Bio Anti-E2F3 Antibody Picoband® catalog # A03068-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Synonyms
Transcription factor E2F3; E2F-3; E2F3; KIAA0075
Gene Name
E2F3
Gene ID
1871
UniProt
O00716
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human E2F3, which shares 95% amino acid (aa) sequence identity with mouse E2F3.
Clonality
Polyclonal
Tissue Specificity
Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.
Applications
WB
Field of Research
Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Transcription
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Lyophilized
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Function
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity) . .
References & Citations
1. Chen, D., Pacal, M., Wenzel, P., Knoepfler, P. S., Leone, G., Bremner, R. Division and apoptosis of E2f-deficient retinal progenitors. Nature 462: 925-929, 2009. 2. Chong, J.-L., Wenzel, P. L., Saenz-Robles, M. T., Nair, V., Ferrey, A., Hagan, J. P., Gomez, Y. M., Sharma, N., Chen, H.-Z., Ouseph, M., Wang, S.-H., Trikha, P., and 10 others. E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature 462: 930-934, 2009.
Storage Conditions
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Calculated Molecular Weight
49162 MW
Observed Molecular Weight
70 kDa
Gene Name Synonym
Transcription factor E2F3
Subcellular Location
Nucleus.
Protein Name
Transcription factor E2F3
Isotype
Rabbit IgG
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Related Products

CatalogName
PA2142Anti-Transcription factor E2F3 E2F3 Antibody Picoband®
PA2142-carrier-freeAnti-Transcription factor E2F3 E2F3 Antibody Picoband®, Carrier-free
PA2142-APCAnti-Transcription factor E2F3 E2F3 Antibody Picoband®, APC Conjugate
PA2142-Dylight488Anti-Transcription factor E2F3 E2F3 Antibody Picoband® (Dylight488 Conjugate)
PA2142-Fluoro594Anti-Transcription factor E2F3 E2F3 Antibody Picoband® Fluoro594 Conjugated
PA2142-Fluoro550Anti-Transcription factor E2F3 E2F3 Antibody Picoband® Fluoro550 Conjugated
PA2142-Fluoro488Anti-Transcription factor E2F3 E2F3 Antibody Picoband® Fluoro488 Conjugated
PA2142-Dylight550Anti-Transcription factor E2F3 E2F3 Antibody Picoband®, Dylight550 Conjugate
PA2142-FITCAnti-Transcription factor E2F3 E2F3 Antibody Picoband®, FITC Conjugate
PA2142-BiotinAnti-Transcription factor E2F3 E2F3 Antibody Picoband® (Biotine Conjugate)

Alternative Products

CatalogName
MBS1755178-01Anti-E2F3 Antibody Picoband
A03068-4Anti-E2F3 Antibody Picoband®
PA2142Anti-Transcription factor E2F3 E2F3 Antibody Picoband®
MBS1754977-01Anti-UCP3 Antibody Picoband
MBS1755705-01Anti-TRIL Antibody Picoband
MBS1755704-01Anti-RBM28 Antibody Picoband
MBS1755689-01Anti-SLC25A23 Antibody Picoband
MBS1750644-01Anti-PSD Picoband Antibody
MBS1755682-01Anti-TREML2 Antibody Picoband
MBS1754974-01Anti-COL4A3 Antibody Picoband

Popular Products