Products for Research Use Only
RegisterLogin

Anti-Cd63 Antibody

CAT: 0519-A01080-1Size: 100 µg/VialDry Ice: NoHazardous: No
Product image 1Product image 2
1 / 2
CAT#:0519-A01080-1Size:100 µg/Vial
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CD63 antigen is a protein that in humans is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It is mapped to 12q13.2. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression.
Description
Boster Bio Anti-Cd63 Antibody Picoband® catalog # A01080-1. Tested in IHC applications. This antibody reacts with Mouse, Rat.
Synonyms
Myosin-binding protein C, cardiac-type; Cardiac MyBP-C; C-protein, cardiac muscle isoform; MYBPC3
Gene Name
Cd63
Gene ID
12512
UniProt
P41731
Host
Rabbit
Reactivity
Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse Cd63, which shares 81.3% and 100% amino acid (aa) sequence identity with human and rat Cd63, respectively.
Clonality
Polyclonal
Tissue Specificity
Red blood cells.
Applications
IHC
Field of Research
Cardiovascular, Contractility, Hypertrophy
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Form
Lyophilized
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
References & Citations
1. Entrez Gene: CD63 CD63 molecule. 2. Gwynn, B., Eicher, E. M., Peters, L. L. Genetic localization of Cd63, a member of the transmembrane 4 superfamily, reveals two distinct loci in the mouse genome. Genomics 35: 389-391, 1996.
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
160 kDa
Gene Name Synonym
Myosin binding protein C, cardiac
Isotype
Rabbit IgG
Contents
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Related Products

CatalogName
A01080Anti-CD63 antigen CD63 Antibody
M01080-4-20μlAnti-CD63 Rabbit Monoclonal Antibody
M01080-4-200μlAnti-CD63 Rabbit Monoclonal Antibody
M01080-4-40μlAnti-CD63 Rabbit Monoclonal Antibody
M01080-1Anti-CD63 Rabbit Monoclonal Antibody
M01080-4-100μlAnti-CD63 Rabbit Monoclonal Antibody
M01080-2Anti-Hu CD63 Purified Monoclonal Antibody
M01080-1-carrier-freeAnti-CD63 Rabbit Monoclonal Antibody, Carrier-free
LS000967-100ugCD63 (NM_001780) Human Over-expression Lysate
LS000967-20ugCD63 (NM_001780) Human Over-expression Lysate

Alternative Products

CatalogName
MBS9510639-01Anti-CD63 Antibody [ABT-CD63]
MBS8309894-01Anti-CD63 Antibody
TMAB-04046-01Anti-CD63 Antibody (5Y709)
TMAY-01813-01Anti-CD63 Antibody (1X871)
MBS1758149-01Anti-Cd63 Antibody Picoband
GTR18083355Anti-CD63

Popular Products