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SGK1 Polyclonal Antibody

CAT: 0749-ABP0118Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP0118Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SGK1 encodes a serine/threonine-protein kinase Sgk1 kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Description
Rabbit Anti-SGK1 Polyclonal Antibody
Product Name Alternative
SGK1; SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1
Gene ID
6446
Accession Number
O00141
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human SGK1 around the non-phosphorylation site of S422
Clonality
Polyclonal
Tag
Serine threonine-protein kinase Sgk1
Applications
IF, WB, IHC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
57kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SGK1 Polyclonal Antibody detects endogenous levels of SGK1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; Not yet tested in other applications
Other Product Names
SGK1; SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O00141
Isotype
Rabbit IgG

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