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Margetuximab

CAT: 0804-HY-P99030-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99030-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Margetuximab (MGAH22) is a chimeric anti-HER2 monoclonal antibody optimized Fc domain, with an EC50 value of 39.33 ng/mL. Margetuximab can be used for researching metastatic HER2-positive breast cancer[1].
CAS Number
1350624-75-7
Product Name Alternative
MGAH-22
UNSPSC
12352203
Target
EGFR
Type
Inhibitory Antibodies
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/margetuximab.html
Purity
99.0
Solubility
H2O
Smiles
[Margetuximab]
Molecular Weight
(146.1 kDa)
References & Citations
[1]Nordstrom JL, et al. Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties. Breast Cancer Res. 2011;13 (6) :R123. doi:10.1186/bcr3069
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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