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Rabbit Polyclonal Antibody to SETD7

CAT: 1725-P42825-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P42825-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule in an unusual conformation binds, a narrow substrate-specific channel that only unmethylated lysine residues can access and a catalytic tyrosine residue.
Product Name Alternative
KMT7; SET7; SET9; SET7/9
Swiss Prot
Q8WTS6
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein corresponding to residues near the C terminal of human SET domain containing (lysine methyltransferase) 7
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
SETD7

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NBP2-20319Rabbit Polyclonal SETD7 Antibody
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