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4-Hydroxyantipyrine

CAT: 0804-HY-B2150-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2150-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine , can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain[1][2].
CAS Number
1672-63-5
Product Name Alternative
4-Hydroxyphenazone; NSC 174055
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-hydroxyantipyrine.html
Purity
99.9
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(C2=CC=CC=C2)N(C)C(C)=C1O
Molecular Formula
C11H12N2O2
Molecular Weight
204.23
Precautions
H315, H319, H335
References & Citations
[1]Ohkawa Y, et al. Effects of 4-hydroxyantipyrine and its 4-O-sulfate on antipyrine as biodistribution promoter. Biol Pharm Bull. 2001 May;24 (5) :529-34.|[2]Ohkawa Y, et al. Application of 4-hydroxyantipyrine and acetaminophen O-sulfate as biodistribution promoter. Biol Pharm Bull. 2001 Dec;24 (12) :1404-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported