Daidzin

• Description :

  Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption[1].

• Product Name Alternative :

  Daidzoside; NPI-031D; Daidzein 7-O-glucoside

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Aldehyde Dehydrogenase (ALDH) ; Mitochondrial Metabolism; Reverse Transcriptase

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research :

  Others; Cardiovascular Disease; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Daidzin.html

• Purity :

  99.77

• Solubility :

  DMSO : ≥ 200 mg/mL

• Smiles :

  OC1=CC=C(C2=COC(C=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C=C4)=C4C2=O)C=C1

• Molecular Formula :

  C21H20O9

• Molecular Weight :

  416.38

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Xie CI, et al. Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication. Alcohol Clin Exp Res. 1994 Dec;18 (6) :1443-7.|[2]Keung WM, et al. Kudzu root: an ancient Chinese source of modern antidipsotropic agents. Phytochemistry. 1998 Feb;47 (4) :499-506.|[3]Keung WM, et al. Daidzin inhibits mitochondrial aldehyde dehydrogenase and suppresses ethanol intake of Syrian golden hamsters. Proc Natl Acad Sci U S A. 1997 Mar 4;94 (5) :1675-9.|[4]Keung WM, Vallee BL. Daidzin and its antidipsotropic analogs inhibit serotonin and dopamine metabolism in isolated mitochondria. Proc Natl Acad Sci U S A. 1998 Mar 3;95 (5) :2198-203.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Phase 1

• CAS Number :

  [552-66-9]