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Rabbit Polyclonal Antibody to E2F5 (N-term)

CAT: 1725-P34408-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P34408-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.
Product Name Alternative
Transcription factor E2F5, E2F-5, E2F5
Swiss Prot
Q15329
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This E2F5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
E2F5 (N-term)
Bands Size
37.6kDa

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