Products for Research Use Only
RegisterLogin

Rabbit Polyclonal Antibody to CHM

CAT: 1725-P32351-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1725-P32351-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD) . This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Name Alternative
Rab proteins geranylgeranyltransferase component A 1, Choroideremia protein, Rab escort protein 1, REP-1, TCD protein, CHM, REP1, TCD
Swiss Prot
P24386
Host
Rabbit
Reactivity
Human
Immunogen
This CHM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-320 amino acids from the Central region of human CHM.
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
CHM
Bands Size
73.5kDa

Related Products

CatalogName
P18959-01Rabbit Monoclonal to CHM
P42541-01Rabbit Polyclonal Antibody to CHML
P10333-01Rabbit Polyclonal Antibody to RAB3IP
P42972-01Rabbit Polyclonal Antibody to EYFP Rabbit
P42971-01Rabbit Polyclonal Antibody to ECFP Rabbit
P12107-01Rabbit Polyclonal Antibody to RNF5
P12101-01Rabbit Polyclonal Antibody to RCC1
P12092-01Rabbit Polyclonal Antibody to RAB24
P12085-01Rabbit Polyclonal Antibody to PUS10
P12074-01Rabbit Polyclonal Antibody to PPOX

Alternative Products

CatalogName
MBS9465999-01Rabbit Polyclonal Antibody PC4 Rabbit Polyclonal Antibody
MBS9465163-01Rabbit Polyclonal Antibody PC1 Rabbit Polyclonal Antibody
TA421149Anti- Rabbit Polyclonal Antibody Rabbit Polyclonal Antibody
53940-01Rabbit Polyclonal AntibodyPC1 Rabbit Polyclonal Antibody
54946-01Rabbit Polyclonal AntibodyPC4 Rabbit Polyclonal Antibody
TA397120Rabbit Polyclonal Antibody

Popular Products