Teprenone Impurity 5

• Description:

  Teprenone Impurity 5 (5Z-GGA) is the cis-isomer of Teprenone (HY-B0779) . Teprenone Impurity 5 has inhibitory activity on the proliferation of human ovarian cancer cells Caov-3, and can block the invasion process of cancer cells. Teprenone Impurity 5 can induce the expression of heat shock protein 70 (HSP70) and thioredoxin (Trx) . Teprenone Impurity 5 can be used for the research of ovarian cancer[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Drug Isomer; HSP; TrxR

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

• Field of Research:

  Cancer

• Smiles:

  C/C (C) =C\CC/C (C) =C\CC/C (C) =C\CC/C (C) =C\CCC (C) =O

• Molecular Formula:

  C23H38O

• Molecular Weight:

  330.55

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Xizhen Zhu, et al. Application of teprenone and derivatives thereof in preparation of medicines for preventing and treating ovarian cancer. CN110882237A. 2020-03-17

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3796-67-6