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Flindersine

CAT: 0804-HY-W984782Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W984782Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flindersine is an antidiabetic and antioxidant agent. Flindersine can result in a decline of blood glucose levels in rats. Flindersine also reduces the body weight gain, plasma insulin concentration, urea, creatinine, total cholesterol, triglycerides and free fatty acids levels in vivo. Flindersine enhances the phophotylation of GLUT4, AMPK, and PPARγ in adipose tissues and skeletal muscles[1].
CAS Number
523-64-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
AMPK; GLUT; PPAR; Reactive Oxygen Species (ROS)
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C1NC2=C(C3=C1C=CC(C)(C)O3)C=CC=C2
Molecular Formula
C14H13NO2
Molecular Weight
227.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Irudayaraj, S. S., et al., (2022) . Antidiabetic with antilipidemic and antioxidant effects of flindersine by enhanced glucose uptake through GLUT4 translocation and PPARγ agonism in type 2 diabetic rats. Journal of ethnopharmacology, 285, 114883.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
GTR19228974-01Flindersine

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